Tetrapyrroles and derivatives
Selleck Chemical LLC Methylcobalamin S4994-25mg
Methylcobalamin (Mecobalamin Vancomin Methycobal Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism It is used to treat some nutritional diseases and other diseases in clinic such as Alzheimer s disease and rheumatoid arthritis
Medchemexpress LLC Biotin-vitamin B12 | 98.4% | 1581.66 | C73H102CoN16O16PS | 10 MG
Biotin-Vitamin B12 is a biotinylated form of cyanocobalamin (vitamin B12) used as a biochemical reagent and affinity probe. The biotin tag enables capture or detection with streptavidin/avidin systems. Supplied as a solid with high purity, it is formulated for in vitro use and can be prepared for in vivo dosing following manufacturer guidance.
Medchemexpress LLC HIF-1 alpha (556-574) | 1201633-99-9 | 99.4% | 2256.54 | 5 MG
HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Abcam 3-Morpholinosydnonimine hydrochloride (SIN-1 hydrochloride), Vasodilator, 20MG
MW 206.63 Da, Purity >99%. Releases NO, superoxide and peroxynitrite under physiological conditions. Potent vasodilator and inhibitor of platelet aggregation. Active metabolite of molsidomine (ab142914). Protective in myocardial ischemia-reperfusion. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Phthalocyanine | 574-93-6 | 98.0% | 10 G
Phthalocyanine is a dark purple to black macrocyclic organic dye and photosensitizer supplied as a solid for laboratory research, with properties suitable for photodynamic and materials studies.
- Solid, dark purple to black appearance.
- Molecular formula C32H18N8; molecular weight 514.54 g/mol.
- Purity 98.0% as specified by the SDS.
- Suitable for photodynamic and materials research applications.
- Available as a 10 G pack size for laboratory use.
Abcam (R)-CPPene (SDZ EAA 494), competitive NMDA antagonist, 10MG
MW 250.19 Da, Purity >98%. Potent competitive NMDA antagonist. Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Zinc phthalocyanine | 14320-04-8 | 98.0% | 577.90 | 25 G
Zinc phthalocyanine (ZnPc) is commonly applied in industry as catalysts and photoconductors, and in biomedical fields such as photodynamic therapy (PDT). It can be used to photooxidise cyclohexane and shows promise for solar-cell applications.
- Commonly applied in industry (catalysts, photoconductors)
- Applied in biomedical fields (photodynamic therapy, PDT)
- Can be used to photooxidise cyclohexane
- Promising for research of solar-cell applications
- Inhibits the growth of cancer cells Kyse-140 and OE-33
- Acts as a photosensitizer that produces ROS under specific light irradiation, impairs mitochondrial membrane integrity, activates caspase-3, and induces apoptosis
Abcam 4-Thiouridine, RNA synthesis inhibitor, 100MG
MW 260.27 Da, Purity >99%. Ribonucleoside (Uridine ab143255) analog. Antisense agent. RNA synthesis inhibitor. Modifies oligos slated for RNA. Induces p53 and inhibits proliferation. Metabolically labels RNA for stability studies.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5-Aza-2'-deo x ycytidine (Decitabine), DNMT1 inhibitor, 25MG
MW 228.21 Da, Purity >99%. Potent DNA methyltransferase 1 (DNMT1) inhibitor (IC₅₀ = 0.2 μM). Incorporated into DNA, inhibits DNMT1 activity to induce DNA hypomethylation. Interferes with protein synthesis. Shows antimetabolic and anticancer activities in vitro. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R)-CPP (mM/ml), NMDA antagonist, 10MM_ML
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB431542, ALK inhibitor, 1MG
MW 384.4 Da, Purity >99%. Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC₅₀ = 94 nM), and 7.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Cobalt phthalocyanine | 3317-67-7 | 98.0% | 571.46 | 1 G
Cobalt phthalocyanine acts as a catalyst in redox reactions, specifically facilitating the aerobic regeneration of aldehydes and ketones from aldoximes and ketoximes. It is also suitable for use in the development of electrocatalysts. This compound has demonstrated the ability to reduce carbon dioxide to carbon monoxide with high activity across a broad pH range, from 4 to 14.
- Catalyzes aerobic regeneration of carbonyl compounds.
- Aids in the development of electrocatalysts.
- Effective in reducing carbon dioxide to carbon monoxide.
- Maintains high activity over a wide pH range.
Abcam A 943931 dihydrochloride, H4 receptor antagonist, 50MG
MW 368.3 Da, Purity >99%. Potent and selective H4 receptor antagonist (pKi = 7-8). Shows anti-inflammatory and analgesic effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (R)-CPP, NMDA antagonist, 50MG
MW 252.2 Da. Highly potent, competitive NMDA antagonist; more active enantiomer of (RS)-CPP (ab120160). (Ki values are 0.04, 0.3, 0.6 and 2.0 μM at NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB-3CT, MMP-2 and MMP-9 inhibitor, 5MG
MW 306.4 Da, Purity >98%. Potent, competitive and non-selective MMP-2 and MMP-9 inhibitor (Ki values are 13.9 and 600 nM for MMP-2 and MMP-9 respectively). Does not alter the activity of MMP-1, MMP-3 or MMP-7 (Ki values are 206 (MMP-1), 15 (MMP-3) and 96 (MMP-7) μM). Neuroprotective and blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement